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Best Seller Polynase D – ointment

Polynase D – ointment

Mandelic Acid

Mandelic Acid

2%

Niacinamide

Niacinamide

2%

Acnil DcX

Acnil DcX

1%

Salicylic Acid

Salicylic Acid

1%

Azelaic Acid

Azelaic Acid

0.5%

Glowsphere BD

Glowsphere BD

0.25%

Glowsphere WD

Glowsphere WD

0.25%

Glowsphere RD

Glowsphere RD

0.25 %

Dosage Form & Strength

Dosage Form & Strength

HS

Adverse Effects

Ocular discomfort, keratitis, and eye irritation may occur

Mechanism of Action

Antibacterial & Anti-inflammatory

Drug Use in Pregnancy

Pregnancy & Lactation Chloramphenicol may be absorbed systemically following the use of the eye ointment. Chloramphenicol does cross the placenta and enter breast milk. Therefore chloramphenicol eye ointment should not be used during pregnancy and breastfeeding. Dexamethasone: Pregnancy: There are no or limited amount of data from the use of Dexamethasone in pregnant woman. Studies in animals have shown reproductive toxicity. Even though, the maximum daily dose (2x 30μl drops x 4 times per day = about 0.240 mg/day dexamethasone) following topical application is much lower than a standard systemic anti-inflammatory dose of about 0.5 to 10mg daily. Dexamethasone is not recommended during pregnancy unless the clinical condition of the woman requires treatment with Dexamethasone. Lactation Systemically administered corticosteroids appear in human milk in quantities that could affect the child being breastfed. However, when instilled topically, systemic exposure is low. It is unknown whether Dexamethasone is excreted in human milk. A risk to the suckling child cannot be excluded. A decision must be made whether to discontinue breast-feeding or to discontinue/abstain from Dexamethasone therapy taking into account the benefit of breast-feeding for the child and the benefit of therapy for the woman.

Drug Use in Pediatric Population

Dexamethasone: Paediatric patients The safety and efficacy of this product has not been established in children below 2 years of age.

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