Relugolix
40mg
Estradiol
1mg
NETA
0.5mg
Dosage Form & Strength
1 tab OD Relugolix 61.5h - Half Life
Endometriosis/Fibroids
Pregnancy, thromboembolic disease, osteoporosis
Hot flush, headache, mood changes
Bone loss risk
P-gp/CYP3A interactions
GnRH antagonist suppresses LH/FSH
Hormonal suppression
BA 12% relugolix Absorption CYP3A Metabolism Feces>Urine Excretion
Contraindicated
Caution ESRD
Avoid severe impairment
Not indicated
Use with caution
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